Network-based screening identifies sitagliptin as an antitumor drug targeting dendritic cells

Background Dendritic cell (DC)-mediated antigen presentation is essential for the priming and activation of tumor-specific T cells. However, few drugs that specifically manipulate DC functions are available. The identification of drugs targeting DC holds great promise for cancer immunotherapy.Method...

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Bibliographic Details
Main Authors: Zheng Huang, Jiaqi Zhang, Qi Peng, Lui Ng, Ian-Ian Ng, Tingzhong Tian, Kaimin Xiao, Xiyue Yao, Jianyang Zeng, Haidong Tang
Format: Article
Language:English
Published: BMJ Publishing Group 2024-03-01
Series:Journal for ImmunoTherapy of Cancer
Online Access:https://jitc.bmj.com/content/12/3/e008254.full