Network-based screening identifies sitagliptin as an antitumor drug targeting dendritic cells
Background Dendritic cell (DC)-mediated antigen presentation is essential for the priming and activation of tumor-specific T cells. However, few drugs that specifically manipulate DC functions are available. The identification of drugs targeting DC holds great promise for cancer immunotherapy.Method...
Main Authors: | , , , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
BMJ Publishing Group
2024-03-01
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Series: | Journal for ImmunoTherapy of Cancer |
Online Access: | https://jitc.bmj.com/content/12/3/e008254.full |