LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

LINC00460-miR-149-5p/miR-150-5p-Mutant p53 Feedback Loop Promotes Oxaliplatin Resistance in Colorectal Cancer

Oxaliplatin resistance is a major challenge in the clinical treatment for advanced colorectal cancer (CRC). Long non-coding RNAs (lncRNAs) are involved in tumorigenesis and progression as critical regulators, while their potential roles in chemoresistance are poorly understood. In this study, we rep...

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Bibliographic Details
Main Authors: Xiangfeng Meng, Wu Sun, Jing Yu, Yu Zhou, Yuanyuan Gu, Jiayi Han, Likun Zhou, Xiaohong Jiang, Chen Wang
Format: Article
Language:English
Published: Elsevier 2020-12-01
Series:Molecular Therapy: Nucleic Acids
Subjects:
colorectal cancer
oxaliplatin resistance
LINC00460
miR-149-5p
miR-150-5p
ceRNA
Online Access:http://www.sciencedirect.com/science/article/pii/S2162253120303309

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http://www.sciencedirect.com/science/article/pii/S2162253120303309

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