Biosynthesis of plant hemostatic dencichine in Escherichia coli
Biosynthetic pathway of dencichine, a plant derived nature product that has found various pharmacological applications, is still elusive. Here, the authors design artificial pathways through retro-biosynthesis approaches and achieve its efficient production in E. coli by systematic metabolic and enz...
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Bibliographic Details
Main Authors: |
Wenna Li,
Zhao Zhou,
Xianglai Li,
Lin Ma,
Qingyuan Guan,
Guojun Zheng,
Hao Liang,
Yajun Yan,
Xiaolin Shen,
Jia Wang,
Xinxiao Sun,
Qipeng Yuan |
Format: | Article
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Language: | English |
Published: |
Nature Portfolio
2022-09-01
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Series: | Nature Communications
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Online Access: | https://doi.org/10.1038/s41467-022-33255-3
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