Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation

Gut taste receptor type 1 member 3 is an intrinsic regulator of Western diet-induced intestinal inflammation

Abstract Background Long-term intake of a Western diet (WD), characterized by a high-fat content and sugary drinks, is hypothesized to contribute to the development of inflammatory bowel disease (IBD). Despite the identified clinical association, the molecular mechanisms by which dietary changes con...

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Bibliographic Details
Main Authors: Woo-Jeong Shon, Jae Won Song, Seung Hoon Oh, Keon-Hee Lee, Hobin Seong, Hyun Ju You, Je Kyung Seong, Dong-Mi Shin
Format: Article
Language:English
Published: BMC 2023-04-01
Series:BMC Medicine
Subjects:
Butyrate-producing microbes
Clostridia
Gut-taste receptor
Inflammatory bowel disease
Intestinal PPAR-γ
mTOR signaling
Online Access:https://doi.org/10.1186/s12916-023-02848-0

Internet

https://doi.org/10.1186/s12916-023-02848-0

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