Decoding molecular programs in melanoma brain metastases

Decoding molecular programs in melanoma brain metastases

Melanoma brain metastases (MBM) show heterogeneous therapeutic response determined by incompletely understood mechanisms. Here, the authors use a multi-OMICS approach and targeted sequencing (TargetSeq) to decipher programs that may define molecular subsets of MBM and their response to therapy.

Bibliographic Details
Main Authors: Josefine Radke, Elisa Schumann, Julia Onken, Randi Koll, Güliz Acker, Bohdan Bodnar, Carolin Senger, Sascha Tierling, Markus Möbs, Peter Vajkoczy, Anna Vidal, Sandra Högler, Petra Kodajova, Dana Westphal, Friedegund Meier, Frank Heppner, Susanne Kreuzer-Redmer, Florian Grebien, Karsten Jürchott, Torben Redmer
Format: Article
Language:English
Published: Nature Portfolio 2022-11-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-022-34899-x

Internet

https://doi.org/10.1038/s41467-022-34899-x

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