MiR-223 regulates human embryonic stem cell differentiation by targeting the IGF-1R/Akt signaling pathway.

MiR-223 regulates human embryonic stem cell differentiation by targeting the IGF-1R/Akt signaling pathway.

Currently, there are difficulties associated with the culturing of pluripotent human embryonic stem cells (hESCs), and knowledge regarding their regulatory mechanisms is limited. MicroRNAs (miRNAs) regulate gene expression and have critical functions in stem cell self-renewal and differentiation. Mo...

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Bibliographic Details
Main Authors: Yan-Hui Yu, Li Zhang, Deng-Shu Wu, Zheng Zhang, Fang-Fang Huang, Jian Zhang, Xiao-Ping Chen, De-Sheng Liang, Hui Zeng, Fang-Ping Chen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3826748?pdf=render

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http://europepmc.org/articles/PMC3826748?pdf=render

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