MiR-223 regulates human embryonic stem cell differentiation by targeting the IGF-1R/Akt signaling pathway.

Currently, there are difficulties associated with the culturing of pluripotent human embryonic stem cells (hESCs), and knowledge regarding their regulatory mechanisms is limited. MicroRNAs (miRNAs) regulate gene expression and have critical functions in stem cell self-renewal and differentiation. Mo...

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Detaylı Bibliyografya
Asıl Yazarlar: Yan-Hui Yu, Li Zhang, Deng-Shu Wu, Zheng Zhang, Fang-Fang Huang, Jian Zhang, Xiao-Ping Chen, De-Sheng Liang, Hui Zeng, Fang-Ping Chen
Materyal Türü: Makale
Dil:English
Baskı/Yayın Bilgisi: Public Library of Science (PLoS) 2013-01-01
Seri Bilgileri:PLoS ONE
Online Erişim:http://europepmc.org/articles/PMC3826748?pdf=render