Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases
Infections caused by pathogens commonly acquired from consumption of food are not always transmitted by that route. They may also be transmitted through contact to animals, other humans or the environment. Additionally, many outbreaks are associated with food contaminated from these non-food sources...
| Main Authors: | , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2019-06-01
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| Series: | Frontiers in Public Health |
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| Online Access: | https://www.frontiersin.org/article/10.3389/fpubh.2019.00172/full |
| _version_ | 1828756736256770048 |
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| author | Peter Gerner-Smidt John Besser Jeniffer Concepción-Acevedo Jason P. Folster Jasmine Huffman Lavin A. Joseph Zuzana Kucerova Megin C. Nichols Colin A. Schwensohn Beth Tolar |
| author_facet | Peter Gerner-Smidt John Besser Jeniffer Concepción-Acevedo Jason P. Folster Jasmine Huffman Lavin A. Joseph Zuzana Kucerova Megin C. Nichols Colin A. Schwensohn Beth Tolar |
| author_sort | Peter Gerner-Smidt |
| collection | DOAJ |
| description | Infections caused by pathogens commonly acquired from consumption of food are not always transmitted by that route. They may also be transmitted through contact to animals, other humans or the environment. Additionally, many outbreaks are associated with food contaminated from these non-food sources. For this reason, such presumed foodborne outbreaks are best investigated through a One Health approach working across human, animal and environmental sectors and disciplines. Outbreak strains or clones that have propagated and continue to evolve in non-human sources and environments often show more sequence variation than observed in typical monoclonal point-source outbreaks. This represents a challenge when using whole genome sequencing (WGS), the new gold standard for molecular surveillance of foodborne pathogens, for outbreak detection and investigation. In this review, using recent examples from outbreaks investigated in the United States (US) some aspects of One Health approaches that have been used successfully to solve such outbreaks are presented. These include using different combinations of flexible WGS based case definition, efficient epidemiological follow-up, traceback, surveillance, and testing of potential food and environmental sources and animal hosts. |
| first_indexed | 2024-12-10T23:20:55Z |
| format | Article |
| id | doaj.art-5f45aac2807046ef8b7f367bb7dabbb3 |
| institution | Directory Open Access Journal |
| issn | 2296-2565 |
| language | English |
| last_indexed | 2024-12-10T23:20:55Z |
| publishDate | 2019-06-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Public Health |
| spelling | doaj.art-5f45aac2807046ef8b7f367bb7dabbb32022-12-22T01:29:43ZengFrontiers Media S.A.Frontiers in Public Health2296-25652019-06-01710.3389/fpubh.2019.00172464818Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne DiseasesPeter Gerner-Smidt0John Besser1Jeniffer Concepción-Acevedo2Jason P. Folster3Jasmine Huffman4Lavin A. Joseph5Zuzana Kucerova6Megin C. Nichols7Colin A. Schwensohn8Beth Tolar9The Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Outbreak Response and Prevention Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Outbreak Response and Prevention Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesThe Enteric Diseases Laboratory Branch, Centers for Disease Control and Prevention, Atlanta, GA, United StatesInfections caused by pathogens commonly acquired from consumption of food are not always transmitted by that route. They may also be transmitted through contact to animals, other humans or the environment. Additionally, many outbreaks are associated with food contaminated from these non-food sources. For this reason, such presumed foodborne outbreaks are best investigated through a One Health approach working across human, animal and environmental sectors and disciplines. Outbreak strains or clones that have propagated and continue to evolve in non-human sources and environments often show more sequence variation than observed in typical monoclonal point-source outbreaks. This represents a challenge when using whole genome sequencing (WGS), the new gold standard for molecular surveillance of foodborne pathogens, for outbreak detection and investigation. In this review, using recent examples from outbreaks investigated in the United States (US) some aspects of One Health approaches that have been used successfully to solve such outbreaks are presented. These include using different combinations of flexible WGS based case definition, efficient epidemiological follow-up, traceback, surveillance, and testing of potential food and environmental sources and animal hosts.https://www.frontiersin.org/article/10.3389/fpubh.2019.00172/fullwhole genome sequencing (WGS)outbreakone healthzoonoticfoodenvironment |
| spellingShingle | Peter Gerner-Smidt John Besser Jeniffer Concepción-Acevedo Jason P. Folster Jasmine Huffman Lavin A. Joseph Zuzana Kucerova Megin C. Nichols Colin A. Schwensohn Beth Tolar Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases Frontiers in Public Health whole genome sequencing (WGS) outbreak one health zoonotic food environment |
| title | Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases |
| title_full | Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases |
| title_fullStr | Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases |
| title_full_unstemmed | Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases |
| title_short | Whole Genome Sequencing: Bridging One-Health Surveillance of Foodborne Diseases |
| title_sort | whole genome sequencing bridging one health surveillance of foodborne diseases |
| topic | whole genome sequencing (WGS) outbreak one health zoonotic food environment |
| url | https://www.frontiersin.org/article/10.3389/fpubh.2019.00172/full |
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