Specific insulin and proinsulin secretion in glucokinase-deficient individuals

Glucokinase (GCK) is an enzyme that regulates insulin secretion, keeping glucose levels within a narrow range. Mutations in the glucokinase gene cause a rare form of diabetes called maturity-onset diabetes of the young (MODY). An early onset (less than 25 years), autosomal dominant inheritance and l...

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Bibliographic Details
Main Authors: V.C. Pardini, G. Velho, R. Reis, S. Purisch, H. Blanché, J.G.H. Vieira, R.C.S. Moisés
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 1999-04-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X1999000400008