Epidermal Neuromedin U Attenuates IgE-Mediated Allergic Skin Inflammation.

Although keratinocyte-derived neuropeptide neuromedin U (NMU) mediates the proinflammatory effects of innate-type mast cell activation, no information is available on the physiological roles. Here, to investigate the effects of NMU on IgE-mediated allergic skin inflammation, we determined whether Ig...

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Bibliographic Details
Main Authors: Yoshiko Mizukawa, Takaaki Doi, Yoshimi Yamazaki, Akihiko Kudo, Tetsuo Shiohara
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4963095?pdf=render