The Synergistic Effect of Proanthocyanidin and HDAC Inhibitor Inhibit Breast Cancer Cell Growth and Promote Apoptosis

The Synergistic Effect of Proanthocyanidin and HDAC Inhibitor Inhibit Breast Cancer Cell Growth and Promote Apoptosis

Histone deacetylase inhibitor (HDACi) is a drug mainly used to treat hematological tumors and breast cancer, but its inhibitory effect on breast cancer falls short of expectations. Grape seed proanthocyanidin extract (GSPE) with abundant proanthocyanidins (PAs) has been explored for its inhibition o...

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Bibliographic Details
Main Authors: Tsz Ki Wang, Shaoting Xu, Yuanjian Fan, Jing Wu, Zilin Wang, Yue Chen, Yunjian Zhang
Format: Article
Language:English
Published: MDPI AG 2023-06-01
Series:International Journal of Molecular Sciences
Subjects:
histone deacetylase inhibitor
breast cancer
proanthocyanidins
synergistic effect
cell proliferation
apoptosis
Online Access:https://www.mdpi.com/1422-0067/24/13/10476

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https://www.mdpi.com/1422-0067/24/13/10476

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