The Induction of Antigen 85B-Specific CD8<sup>+</sup> T Cells by Recombinant BCG Protects against Mycobacterial Infection in Mice

<i>Mycobacterium tuberculosis</i> (Mtb) infection remains a major health problem worldwide. Although the Bacillus Calmette-Guérin (BCG) vaccine is the most widely used vaccination for preventing tuberculosis (TB), its efficacy is limited. We previously developed a new recombinant BCG (rB...

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Bibliographic Details
Main Authors: Shihoko Komine-Aizawa, Satoru Mizuno, Akira Kawano, Satoshi Hayakawa, Kazuhiro Matsuo, Mitsuo Honda
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:International Journal of Molecular Sciences
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Online Access:https://www.mdpi.com/1422-0067/24/2/966