Class 3 semaphorins negatively regulate dermal lymphatic network formation

The development of a patterned lymphatic vascular network is essential for proper lymphatic functions during organ development and homeostasis. Here we report that class 3 semaphorins (SEMA3s), SEMA3F and SEMA3G negatively regulate lymphatic endothelial cell (LEC) growth and sprouting to control der...

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Bibliographic Details
Main Authors: Yutaka Uchida, Jennifer M. James, Fumikazu Suto, Yoh-suke Mukouyama
Format: Article
Language:English
Published: The Company of Biologists 2015-09-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/4/9/1194