Class 3 semaphorins negatively regulate dermal lymphatic network formation
The development of a patterned lymphatic vascular network is essential for proper lymphatic functions during organ development and homeostasis. Here we report that class 3 semaphorins (SEMA3s), SEMA3F and SEMA3G negatively regulate lymphatic endothelial cell (LEC) growth and sprouting to control der...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
The Company of Biologists
2015-09-01
|
Series: | Biology Open |
Subjects: | |
Online Access: | http://bio.biologists.org/content/4/9/1194 |