Fbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells

Fbxw11 impairs the repopulation capacity of hematopoietic stem/progenitor cells

Abstract Background The ubiquitin–proteasome system plays important roles in maintaining the self-renewal and differentiation of stem and progenitor cells through highly ordered degradation of cellular proteins. Fbxw11, an E3 ligase, participates in many important biological processes by targeting a...

Full description

Bibliographic Details
Main Authors: Lina Wang, Yongjun Piao, Dongyue Zhang, Wenli Feng, Chenchen Wang, Xiaoxi Cui, Qian Ren, Xiaofan Zhu, Guoguang Zheng
Format: Article
Language:English
Published: BMC 2022-06-01
Series:Stem Cell Research & Therapy
Subjects:
Fbxw11
Hematopoietic stem cell
Hematopoietic progenitor cell
Single-cell RNA sequencing
Online Access:https://doi.org/10.1186/s13287-022-02926-9

Internet

https://doi.org/10.1186/s13287-022-02926-9

Similar Items