Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells

Quantitative proteomics reveal lineage-specific protein profiles in iPSC-derived Marfan syndrome smooth muscle cells

Abstract Marfan syndrome (MFS) is a connective tissue disorder caused by mutations in the FBN1 gene that produces wide disease phenotypic variability. The lack of ample genotype–phenotype correlation hinders translational study development aimed at improving disease prognosis. In response to this ne...

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Bibliographic Details
Main Authors: Cristiana Iosef, Albert J. Pedroza, Jason Z. Cui, Alex R. Dalal, Mamoru Arakawa, Yasushi Tashima, Tiffany K. Koyano, Grayson Burdon, Samantha M. P. Churovich, Joshua O. Orrick, Mitchel Pariani, Michael P. Fischbein
Format: Article
Language:English
Published: Nature Portfolio 2020-11-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-77274-w

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https://doi.org/10.1038/s41598-020-77274-w

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