A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against <i>Staphylococcus aureus</i> In Vitro and In Vivo

A Highly Active Chimeric Lysin with a Calcium-Enhanced Bactericidal Activity against <i>Staphylococcus aureus</i> In Vitro and In Vivo

Lysins, including chimeric lysins, have recently been explored as novel promising alternatives to failing antibiotics in treating multi-drug resistant (MDR) pathogens, including methicillin-resistant <i>Staphylococcus aureus</i> (MRSA). Herein, by fusing the CHAP (cysteine, histidine-dep...

Full description

Bibliographic Details
Main Authors: Xiaohong Li, Shujuan Wang, Raphael Nyaruaba, Huan Liu, Hang Yang, Hongping Wei
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Antibiotics
Subjects:
<i>Staphylococcus aureus</i>
lysin
bactericidal activity
calcium
bacteremia
ClyC
Online Access:https://www.mdpi.com/2079-6382/10/4/461

Internet

https://www.mdpi.com/2079-6382/10/4/461

Similar Items