Exosomes derived from miR-338-3p-modified adipose stem cells inhibited inflammation injury of chondrocytes via targeting RUNX2 in osteoarthritis

Exosomes derived from miR-338-3p-modified adipose stem cells inhibited inflammation injury of chondrocytes via targeting RUNX2 in osteoarthritis

Abstract Background Osteoarthritis (OA) is a chronic degenerative disease that is one of the main causes of disability in middle-aged and elderly people. Adipose stem cell (ASC)-derived exosomes (ASC-Exo) could repair cartilage damage and treat OA. MiRNA-338-3p expression was confirmed to play a rol...

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Bibliographic Details
Main Authors: ChunLiang Li, Wei Li, GengZang Pu, JingWen Wu, Feng Qin
Format: Article
Language:English
Published: BMC 2022-12-01
Series:Journal of Orthopaedic Surgery and Research
Subjects:
Osteoarthritis
Exosomes
miR-338-3p
Mesenchymal stem cells from adipose tissue
Online Access:https://doi.org/10.1186/s13018-022-03437-2

Internet

https://doi.org/10.1186/s13018-022-03437-2

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