Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice

Beneficial Effects of Celastrol on Immune Balance by Modulating Gut Microbiota in Experimental Ulcerative Colitis Mice

Ulcerative colitis (UC) is a chronic inflammatory bowel disease caused by many factors including colonic inflammation and microbiota dysbiosis. Previous studies have indicated that celastrol (CSR) has strong anti-inflammatory and immune-inhibitory effects. Here, we investigated the effects of CSR on...

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Bibliographic Details
Main Authors: Mingyue Li, Weina Guo, Yalan Dong, Wenzhu Wang, Chunxia Tian, Zili Zhang, Ting Yu, Haifeng Zhou, Yang Gui, Kaming Xue, Junyi Li, Feng Jiang, Alexey Sarapultsev, Huafang Wang, Ge Zhang, Shanshan Luo, Heng Fan, Desheng Hu
Format: Article
Language:English
Published: Oxford University Press 2022-04-01
Series:Genomics, Proteomics & Bioinformatics
Subjects:
Ulcerative colitis
Celastrol
Gut microbiota
Treg/Th balance
Metabolomics
Online Access:http://www.sciencedirect.com/science/article/pii/S1672022922000663

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http://www.sciencedirect.com/science/article/pii/S1672022922000663

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