Site-specific structural order in Alzheimer's Aβ42 fibrils

Deposition of amyloid fibrils is a pathological hallmark of Alzheimer's disease. Aβ42 is the major protein whose aggregation leads to the formation of these fibrils. Understanding the detailed structure of Aβ42 fibrils is of particular importance for delineating the mechanism of Aβ42 aggregatio...

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מידע ביבליוגרפי
Main Authors: Hongsu Wang, Yoon Kyung Lee, Christine Xue, Zhefeng Guo
פורמט: Article
שפה:English
יצא לאור: The Royal Society 2018-01-01
סדרה:Royal Society Open Science
נושאים:
גישה מקוונת:https://royalsocietypublishing.org/doi/pdf/10.1098/rsos.180166