Exposure–response analysis using time-to-event data for bevacizumab biosimilar SB8 and the reference bevacizumab

Exposure–response analysis using time-to-event data for bevacizumab biosimilar SB8 and the reference bevacizumab

Purpose: This analysis aimed to characterize the exposure–response relationship of bevacizumab in non-small-cell lung cancer (NSCLC) and evaluate the efficacy of SB8, a bevacizumab biosimilar, and Avastin®, the reference bevacizumab sourced from the European Union (EU), based on the exposure reporte...

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Bibliographic Details
Main Authors: Suemin Park, Jin Ah Jung, Sungil Ju, Hyeong-Seok Lim
Format: Article
Language:English
Published: Frontiers Media S.A. 2024-01-01
Series:Frontiers in Pharmacology
Subjects:
bevacizumab
biosimilar
non-small-cell lung cancer
time-to-event modeling
exposure–response analysis
simulation
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1288308/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2023.1288308/full

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