Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the <i>Burkholderia cepacia</i> Complex

Human Cryptic Host Defence Peptide GVF27 Exhibits Anti-Infective Properties against Biofilm Forming Members of the <i>Burkholderia cepacia</i> Complex

Therapeutic solutions to counter <i>Burkholderia cepacia</i> complex (Bcc) bacteria are challenging due to their intrinsically high level of antibiotic resistance. Bcc organisms display a variety of potential virulence factors, have a distinct lipopolysaccharide naturally implicated in a...

Full description

Bibliographic Details
Main Authors: Andrea Bosso, Rosa Gaglione, Rocco Di Girolamo, Edwin J. A. Veldhuizen, Pilar García-Vello, Salvatore Fusco, Valeria Cafaro, Maria Monticelli, Rosanna Culurciello, Eugenio Notomista, Angela Arciello, Elio Pizzo
Format: Article
Language:English
Published: MDPI AG 2022-02-01
Series:Pharmaceuticals
Subjects:
host defence peptides
antimicrobial peptides
anti-biofilm agents
LPS neutralisation
agglutinating activity
immunomodulatory activities
Online Access:https://www.mdpi.com/1424-8247/15/2/260

Internet

https://www.mdpi.com/1424-8247/15/2/260

Similar Items