The predictive and prognostic role of single nucleotide gene variants of PD-1 and PD-L1 in patients with advanced melanoma treated with PD-1 inhibitors

The predictive and prognostic role of single nucleotide gene variants of PD-1 and PD-L1 in patients with advanced melanoma treated with PD-1 inhibitors

Background: Despite having revolutionized the treatment paradigm for advanced melanoma, not all patients benefit from immune checkpoint inhibitor therapy. To date, there are no predictive biomarkers for response or the occurrence of immune-related adverse events (irAEs) to programmed cell death prot...

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Bibliographic Details
Main Authors: A. Boutros, R. Carosio, D. Campanella, F. Spagnolo, B. Banelli, A. Morabito, M.P. Pistillo, E. Croce, F. Cecchi, P. Pronzato, P. Queirolo, E. Raposio, V. Fontana, E.T. Tanda
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Immuno-Oncology and Technology
Subjects:
melanoma
SNV
single nucleotide gene variant
PD-1
PD-L1
Online Access:http://www.sciencedirect.com/science/article/pii/S2590018823000369

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http://www.sciencedirect.com/science/article/pii/S2590018823000369

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