Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties

Design, Synthesis, In Vitro Biological Activity Evaluation and Stabilized Nanostructured Lipid Carrier Formulation of Newly Synthesized Schiff Bases-Based TMP Moieties

A series of novel Schiff bases-based TMP moieties have been designed and synthesized as potential anticancer agents. The target Schiff bases were screened for their cytotoxic activity against the MDA-MB-231 breast cancer cell line. Most of the tested molecules revealed good cytotoxic activity, espec...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид:	Syed Nasir Abbas Bukhari, Mohamed Y. Zakaria, Muhammad Usman Munir, Naveed Ahmad, Mervat A Elsherif, Rasha Emad Badr, Ahmad Khalaf Hassan, Ali H. Abu Almaaty, Islam Zaki
Формат:	Өгүүллэг
Хэл сонгох:	English
Хэвлэсэн:	MDPI AG 2022-05-01
Цуврал:	Pharmaceuticals
Нөхцлүүд:	TMP Schiff base synthesis cytotoxicity tubulin cell cycle analysis
Онлайн хандалт:	https://www.mdpi.com/1424-8247/15/6/679

Ижил төстэй зүйлс

Design, Synthesis and Cytotoxic Activity Evaluation of Newly Synthesized Amides-Based TMP Moiety as Potential Anticancer Agents over HepG2 Cells
-н: Tarfah Al-Warhi, зэрэг
Хэвлэсэн: (2022-06-01)

Effects of Refiner Plates with Different Fillings on TMP Properties
-н: Hyeong-Hun Park, зэрэг
Хэвлэсэн: (2023-04-01)

TMP-SMX induced type 4 hypersensitivity with multi-organ involvement
-н: Samantha Sircar, зэрэг
Хэвлэсэн: (2023-01-01)

Synthesizing, Characterizing and Studying the Biological Activity of Some New Schiff-Bases Derivatives Containing the Monosaccharide Moiety
-н: Baghdad Science Journal
Хэвлэсэн: (2016-09-01)

A COMPARISON BETWEEN THE EFFECTS OF OZONE AND ALKALINE PEROXIDE TREATMENTS ON TMP PROPERTIES AND SUBSEQUENT LOW CONSISTENCY REFINING
-н: James A. Olson, зэрэг
Хэвлэсэн: (2011-11-01)

Construction and functional verification of size-reduced plasmids based on TMP resistance gene dfrB10
-н: Chun-cao Li, зэрэг
Хэвлэсэн: (2023-12-01)

Tribological Performances of Trimethylolpropane (TMP) Blended with Graphene Oxide Using Four-Ball Tribotester
-н: Zulhanafi Paiman, зэрэг
Хэвлэсэн: (2024-02-01)

Prophylactic antibiotic treatment with TMP-SMX decreased the incidence of interstitial pneumonia in patients with B-cell lymphoma on chemotherapy
-н: Cong Li, зэрэг
Хэвлэсэн: (2020-08-01)

Synthesis and Biological Activity Screening of Newly Synthesized Trimethoxyphenyl-Based Analogues as Potential Anticancer Agents
-н: Tarfah Al-Warhi, зэрэг
Хэвлэсэн: (2022-07-01)

TMP269, a small molecule inhibitor of class IIa HDAC, suppresses RABV replication in vitro
-н: Juanbin Yin, зэрэг
Хэвлэсэн: (2023-12-01)

NbTMP14 Is Involved in Tomato Spotted Wilt Virus Infection and Symptom Development by Interaction with the Viral NSm Protein
-н: Jin Zhan, зэрэг
Хэвлэсэн: (2021-03-01)

Evaluation of Tribological Performance of Hydrogenated Dlc by Surface Texturing in the Presence of Palm Based Tmp Ester at Different Temperatures
-н: Mahendra Varman, зэрэг
Хэвлэсэн: (2019-01-01)

Overexpression of a thylakoid membrane protein gene OsTMP14 improves indica rice cold tolerance
-н: Yongrong Liao, зэрэг
Хэвлэсэн: (2017-07-01)

Synthesis and Spectroscopic Characterization of New Schiff Bases Containing the Benzo-15-Crown-5 Moiety
-н: Hakan Dal, зэрэг
Хэвлэсэн: (2004-09-01)

Evaluating the diagnostic accuracy of TpN17 and TmpA recombinant proteins in syphilis detection: a phase II study
-н: Ângelo Antônio Oliveira Silva, зэрэг
Хэвлэсэн: (2024-02-01)

Epigenetic drug screening identifies enzyme inhibitors A-196 and TMP-269 as novel regulators of sprouting angiogenesis
-н: M. Beter, зэрэг
Хэвлэсэн: (2025-01-01)

Exploration for the opioidergic, GABAergic and histaminergic potentials of synthesized Schiff’s base derivatives: An in-vivo approach
-н: Adnan Khan, зэрэг
Хэвлэсэн: (2024-08-01)

Synthesis, characterization and biological studies on some metal complexes with Schiff base ligand containing pyrazolone moiety
-н: M. Sivasankaran Nair, зэрэг
Хэвлэсэн: (2016-09-01)

Poly(vinyl Chloride) Photostabilization in the Presence of Schiff Bases Containing a Thiadiazole Moiety
-н: Naser Shaalan, зэрэг
Хэвлэсэн: (2018-04-01)

Syntheses, Characterization, Antioxidant Activity, and Toxicity Evaluation of Schiff Base Derivates from O-Vanillin
-н: Ahmad Hanapi, зэрэг
Хэвлэсэн: (2024-04-01)

Polymeric Copper(II) Complexes with a Newly Synthesized Biphenyldicarboxylic Acid Schiff Base Ligand—Synthesis, Structural and Thermal Characterization
-н: Milica G. Bogdanović, зэрэг
Хэвлэсэн: (2022-12-01)

Design and Synthesis of Newly Synthesized Acrylamide Derivatives as Potential Chemotherapeutic Agents against MCF-7 Breast Cancer Cell Line Lodged on PEGylated Bilosomal Nano-Vesicles for Improving Cytotoxic Activity
-н: Islam Zaki, зэрэг
Хэвлэсэн: (2021-10-01)

The first reported pulmonary nocardiosis caused by Nocardia gipuzkoensis resisted to trimethoprim/sulfamethoxazol (TMP-SMZ) in an immunocompetent patient
-н: Yishan Duan, зэрэг
Хэвлэсэн: (2024-06-01)

Azobenzene-Containing Schiff-Bases—Syntheses and Dyes Applications
-н: Estelle Leonard, зэрэг
Хэвлэсэн: (2024-02-01)

Synthesis and Characterization of Novel Schiff Bases of Imide Moiety
-н: Sulaiman M. Hasan, зэрэг
Хэвлэсэн: (2017-04-01)

Neuroprotective mechanism of TMP269, a selective class IIA histone deacetylase inhibitor, after cerebral ischemia/reperfusion injury
-н: Lu Su, зэрэг
Хэвлэсэн: (2020-01-01)

Potentiometric and spectrophotometric studies of the complexation of Schiff-base hydrazones containing the pyrimidine moiety
-н: Seleem H.S., зэрэг
Хэвлэсэн: (2003-01-01)

Synthesis and characterization of palladium(ii) and nickel(ii) schiff base complexes for homogenous catalytic and anticancer studies / Shahrul Nizam Ahmad
-н: Ahmad, Shahrul Nizam
Хэвлэсэн: (2018)

Fabrication of copper-selective PVC membrane electrode based on newly synthesized copper complex of Schiff base as carrier
-н: Sulekh Chandra, зэрэг
Хэвлэсэн: (2016-09-01)

Trimethoprim-sulfamethoxazole-induced Pancytopenia in a Newly Diagnosed HIV Patient
-н: Vikram B. Vikhe, зэрэг
Хэвлэсэн: (2024-08-01)

Antileishmanial Activity of New Synthesized Schiff and Mannich (Morpholine) Base Compounds
-н: Şahin Direkel, зэрэг
Хэвлэсэн: (2020-12-01)

Novel Schiff Bases Derived From Pyromellitic Dianhydride
-н: Athraa M. Saloom, зэрэг
Хэвлэсэн: (2017-04-01)

PREVALENCE OF SYPHILIS AND HIV INFECTION IN BLOOD DONORS IN COSMOPOLITAN LAHORE DURING THE YEAR 2014
-н: Hamid Mahmood, зэрэг
Хэвлэсэн: (2015-12-01)

The Effect of o-Substituents on Mass Spectra of Schiff Bases Synthesized from Salicylaldehyde
-н: Gökhan Denizli, зэрэг
Хэвлэсэн: (2013-06-01)

Unravelling the adsorption and anti-corrosion potency of newly synthesized thiazole Schiff bases on C-steel in 1 M HCl: Computational and experimental implementations
-н: Ahmed A. Farag, зэрэг
Хэвлэсэн: (2025-03-01)

Current Perspectives on Biological Screening of Newly Synthetised Sulfanilamide Schiff Bases as Promising Antibacterial and Antibiofilm Agents
-н: Maria Coanda, зэрэг
Хэвлэсэн: (2024-03-01)

Syntheses and Structural Studies of Schiff Bases Involving Hydrogen Bonds
-н: JosÃƒÂ© Elguero, зэрэг
Хэвлэсэн: (2006-06-01)

Interaction of Phenolic Schiff Bases Bearing Sulfhydryl Moieties with 2,2-Diphenyl-1-picrylhydrazyl Radical: Structure–Activity Relationship Study
-н: Iveta Turomsha, зэрэг
Хэвлэсэн: (2023-11-01)

Anti-Proliferative Activity and Tubulin Targeting of Novel Micro and Nanoparticles Complexes of 4-Amino-3-Thion-1, 2, 4-Triazole Derivatives
-н: Atheer Ali, зэрэг
Хэвлэсэн: (2020-03-01)

Synthesis and characterization of some new Schiff base azo disperse dyes based on chromene moiety for simultaneous dyeing and antimicrobial finishing
-н: Hagar Fathy, зэрэг
Хэвлэсэн: (2024-10-01)