mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines

mRNA-Loaded Lipid Nanoparticles Targeting Immune Cells in the Spleen for Use as Cancer Vaccines

mRNA delivery has recently gained substantial interest for possible use in vaccines. Recently approved mRNA vaccines are administered intramuscularly where they transfect antigen-presenting cells (APCs) near the site of administration, resulting in an immune response. The spleen contains high number...

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Bibliographic Details
Main Authors: Ryoya Shimosakai, Ikramy A. Khalil, Seigo Kimura, Hideyoshi Harashima
Format: Article
Language:English
Published: MDPI AG 2022-08-01
Series:Pharmaceuticals
Subjects:
mRNA
spleen
immune cell
vaccine
lipid nanoparticle
Online Access:https://www.mdpi.com/1424-8247/15/8/1017

Internet

https://www.mdpi.com/1424-8247/15/8/1017

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