Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188

Crystal Structure of SARS-CoV-2 Main Protease in Complex with the Non-Covalent Inhibitor ML188

Viral proteases are critical enzymes for the maturation of many human pathogenic viruses and thus are key targets for direct acting antivirals (DAAs). The current viral pandemic caused by SARS-CoV-2 is in dire need of DAAs. The Main protease (M<sup>pro</sup>) is the focus of extensive st...

Full description

Bibliographic Details
Main Authors: Gordon J. Lockbaum, Archie C. Reyes, Jeong Min Lee, Ronak Tilvawala, Ellen A. Nalivaika, Akbar Ali, Nese Kurt Yilmaz, Paul R. Thompson, Celia A. Schiffer
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Viruses
Subjects:
SARS-CoV-2
Covid-19
main protease
M<sup>pro</sup>
ML188
protease inhibitor
Online Access:https://www.mdpi.com/1999-4915/13/2/174

Internet

https://www.mdpi.com/1999-4915/13/2/174

Similar Items