Towards a hierarchy of mechanisms in CaMKII-mediated arrhythmia

CaMKII activity has been shown to contribute to arrhythmogenesis in a remarkably broad range of cardiac pathologies. Several of these involve significant structural and electrophysiologic remodeling, whereas others are due to specific channelopathies, and are not typically associated with arrhythmog...

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Bibliographic Details
Main Authors: Kevin P Vincent, Andrew D McCulloch, Andrew G Edwards
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2014.00110/full