Transcriptional signatures of human peripheral blood mononuclear cells can identify the risk of tuberculosis progression from latent infection among individuals with silicosis

Transcriptional signatures of human peripheral blood mononuclear cells can identify the risk of tuberculosis progression from latent infection among individuals with silicosis

Host immune factor plays an important role in the progression of latent tuberculosis infection (LTBI) to active tuberculosis (TB) disease. However, whether global gene expression measured in blood biomarkers allows the identification of prospective signatures for TB risk remains unknown. Hence, we a...

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Bibliographic Details
Main Authors: Qiao-ling Ruan, Qing-luan Yang, Yi-xin Gao, Jing Wu, Si-ran Lin, Jing-Yu Zhou, Ling-yun Shao, Sen Wang, Qian-qian Liu, Yan Gao, Ning Jiang, Wen-hong Zhang
Format: Article
Language:English
Published: Taylor & Francis Group 2021-01-01
Series:Emerging Microbes and Infections
Subjects:
Tuberculosis
peripheral blood mononuclear cell
biomarker
latent tuberculosis infection
RNA sequencing
interferon-gamma
Online Access:https://www.tandfonline.com/doi/10.1080/22221751.2021.1915184

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https://www.tandfonline.com/doi/10.1080/22221751.2021.1915184

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