Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Undetected Multidrug-Resistant Tuberculosis Amplified by First-line Therapy in Mixed Infection

Infections with >1 Mycobacterium tuberculosis strain(s) are underrecognized. We show, in vitro and in vivo, how first-line treatment conferred a competitive growth advantage to amplify a multidrug-resistant M. tuberculosis strain in a patient with mixed infection. Diagnostic techniques that ident...

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Bibliographic Details
Main Authors: Suzanne M. Hingley-Wilson, Rosalyn Casey, David Connell, Samuel Bremang, Jason T. Evans, Peter M. Hawkey, Grace E. Smith, Annette Jepson, Stuart Philip, Onn Min Kon, Ajit Lalvani
Format: Article
Language:English
Published: Centers for Disease Control and Prevention 2013-07-01
Series:Emerging Infectious Diseases
Subjects:
Mycobacterium tuberculosis
co-infection
treatment resistance
multidrug resistant
drug sensitive
tuberculosis and other mycobacteria
Online Access:https://wwwnc.cdc.gov/eid/article/19/7/13-0313_article

Internet

https://wwwnc.cdc.gov/eid/article/19/7/13-0313_article

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