The crystal-induced activation of NLRP3 inflammasomes in atherosclerosis

Abstract Atherosclerosis is an inflammatory disease, which is accompanied by the deposition of cholesterol-rich lipids and the infiltration of macrophages. Other well-known features of atherosclerotic lesions include the deposition of cholesterol crystals and calcium phosphate crystals; however, the...

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Bibliographic Details
Main Authors: Tadayoshi Karasawa, Masafumi Takahashi
Format: Article
Language:English
Published: BMC 2017-09-01
Series:Inflammation and Regeneration
Subjects:
Online Access:http://link.springer.com/article/10.1186/s41232-017-0050-9