Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E

Bioactivity-Guided Isolation of Totarane-Derived Diterpenes from Podocarpus neriifolius and Structure Revision of 3-Deoxy-2α-hydroxynagilactone E

Abstract Bioactivity-guided phytochemical investigation of Podocarpus neriifolius D. Don. (Podocarpaceae) has led to the isolation of one new (2) and three known (1, 3, and 4) B-type podolactones, along with three totarane-type diterpenes (5-7). Their structures were determined by interpretation of...

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Bibliographic Details
Main Authors: P. Annécie Benatrehina, Wei-Lun Chen, Austin A. Czarnecki, Steven Kurina, Hee-Byung Chai, Daniel D. Lantvit, Tran N. Ninh, Xiaoli Zhang, Djaja D. Soejarto, Joanna E. Burdette, A. Douglas Kinghorn, L. Harinantenaina Rakotondraibe
Format: Article
Language:English
Published: SpringerOpen 2019-02-01
Series:Natural Products and Bioprospecting
Subjects:
Podocarpus neriifolius
Nagilactone G-2β-O-β-d-glucoside
Hollow fiber assay
3-Deoxy-2α-hydroxynagilactone E
Antiproliferative
B-type podolactone
Online Access:http://link.springer.com/article/10.1007/s13659-019-0198-x

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http://link.springer.com/article/10.1007/s13659-019-0198-x

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