Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation

Ascorbic acid, corticosteroids, and thiamine in sepsis: a review of the biologic rationale and the present state of clinical evaluation

Abstract The combination of thiamine, ascorbic acid, and hydrocortisone has recently emerged as a potential adjunctive therapy to antibiotics, infectious source control, and supportive care for patients with sepsis and septic shock. In the present manuscript, we provide a comprehensive review of the...

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Bibliographic Details
Main Authors: Ari Moskowitz, Lars W. Andersen, David T. Huang, Katherine M. Berg, Anne V. Grossestreuer, Paul E. Marik, Robert L. Sherwin, Peter C. Hou, Lance B. Becker, Michael N. Cocchi, Pratik Doshi, Jonathan Gong, Ayan Sen, Michael W. Donnino
Format: Article
Language:English
Published: BMC 2018-10-01
Series:Critical Care
Subjects:
Thiamine
Ascorbic acid
Corticosteroids
Metabolic resuscitation
Sepsis
Online Access:http://link.springer.com/article/10.1186/s13054-018-2217-4

Internet

http://link.springer.com/article/10.1186/s13054-018-2217-4

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