Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen

Synthesis and Investigation of Anti-Inflammatory Activity of New Thiourea Derivatives of Naproxen

The aim of the study was a synthesis and investigation of the dose-dependent anti-inflammatory effect of new thiourea derivatives of naproxen with selected aromatic amines and esters of aromatic amino acids. The results of the in vivo study indicate that derivatives of <i>m</i>-anisidine...

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Bibliographic Details
Main Authors: Nikola Nedeljković, Vladimir Dobričić, Jelena Bošković, Marina Vesović, Jovana Bradić, Marijana Anđić, Aleksandar Kočović, Nevena Jeremić, Jovana Novaković, Vladimir Jakovljević, Zorica Vujić, Miloš Nikolić
Format: Article
Language:English
Published: MDPI AG 2023-04-01
Series:Pharmaceuticals
Subjects:
naproxen
thiourea
carrageenan
paw edema
anti-inflammatory activity
COX-2
Online Access:https://www.mdpi.com/1424-8247/16/5/666

Internet

https://www.mdpi.com/1424-8247/16/5/666

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