Exploration of Oxygen-Induced Retinopathy Model to Discover New Therapeutic Drug Targets in Retinopathies

Exploration of Oxygen-Induced Retinopathy Model to Discover New Therapeutic Drug Targets in Retinopathies

Oxygen-induced retinopathy (OIR) is a pure hypoxia-driven angiogenesis model and the most widely used model for ischemic retinopathies, such as retinopathy of prematurity (ROP), proliferative diabetic retinopathy (PDR), and retinal vein occlusion (RVO). OIR model has been used to test new potential...

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Bibliographic Details
Main Authors: Maria Vähätupa, Tero A. H. Järvinen, Hannele Uusitalo-Järvinen
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Pharmacology
Subjects:
hypoxia
angiogenesis
vascular permeability
R-Ras
filamin
myosin
Online Access:https://www.frontiersin.org/article/10.3389/fphar.2020.00873/full

Internet

https://www.frontiersin.org/article/10.3389/fphar.2020.00873/full

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