Functional Polyglycidol-Based Block Copolymers for DNA Complexation

Functional Polyglycidol-Based Block Copolymers for DNA Complexation

Gene therapy is an attractive therapeutic method for the treatment of genetic disorders for which the efficient delivery of nucleic acids into a target cell is critical. The present study is aimed at evaluating the potential of copolymers based on linear polyglycidol to act as carriers of nucleic ac...

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Bibliographic Details
Main Authors: Radostina Kalinova, Miroslava Valchanova, Ivaylo Dimitrov, Sevdalina Turmanova, Iva Ugrinova, Maria Petrova, Zlatina Vlahova, Stanislav Rangelov
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:International Journal of Molecular Sciences
Subjects:
gene delivery
non-viral vectors
polyplex formation
polyglycidol copolymers
cationic copolymers
DNA complexation
Online Access:https://www.mdpi.com/1422-0067/22/17/9606

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https://www.mdpi.com/1422-0067/22/17/9606

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