Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway

Myricetin attenuates hypoxic-ischemic brain damage in neonatal rats via NRF2 signaling pathway

Introduction: Hypoxic-ischemic encephalopathy (HIE) is a crucial cause of neonatal death and neurological sequelae, but currently there is no effective therapy drug for HIE. Both oxidative stress and apoptosis play critical roles in the pathological development of HIE. Myricetin, a naturally extract...

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Bibliographic Details
Main Authors: Tingting Chen, Yingying Hu, Liying Lu, Qianlei Zhao, Xiaoyue Tao, Bingqing Ding, Shangqin Chen, Jianghu Zhu, Xiaoling Guo, Zhenlang Lin
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Pharmacology
Subjects:
neonatal hypoxic-ischemic (HI) brain injury
myricetin
oxidative stress
apoptosis
NRF2 signaling pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1134464/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1134464/full

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