Genes related to apoptosis predict necrosis of the liver as a phenotype observed in rats exposed to a compendium of hepatotoxicants

<p>Abstract</p> <p>Background</p> <p>Some of the biochemical events that lead to necrosis of the liver are well-known. However, the pathogenesis of necrosis of the liver from exposure to hepatotoxicants is a complex biological response to the injury. We hypothesize that...

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Bibliographic Details
Main Authors: Zeng Zhao-Bang, Heinloth Alexandra N, Huang Lingkang, Paules Richard S, Bushel Pierre R
Format: Article
Language:English
Published: BMC 2008-06-01
Series:BMC Genomics
Online Access:http://www.biomedcentral.com/1471-2164/9/288