Levistilide A Promotes Expansion of Human Umbilical Cord Blood Hematopoietic Stem Cells by Enhancing Antioxidant Activity

Levistilide A Promotes Expansion of Human Umbilical Cord Blood Hematopoietic Stem Cells by Enhancing Antioxidant Activity

Several approaches to expand human hematopoietic stem cells (hHSCs) clinically along with retainable capability of multipotential differentiation have been reported, but only a few have advanced to evaluation in clinical trials, which limits the application of HSC-based therapy. Here we show a phtha...

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Bibliographic Details
Main Authors: Mei He, Hui Xu, Guangju Liu, Ming Yang, Wenshan Zhang, Yafang Li, Hexiao Zhang, Chaoqun Wang, Yiran Zhang, Xiaolei Liu, Shiqi Xu, Yahui Ding, Yinghui Li, Yingdai Gao, Quan Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-02-01
Series:Frontiers in Pharmacology
Subjects:
natural product
human hematopoietic stem cell
ex vivo expansion
phthalide derivatives
reactive oxygen species (ROS)
Levistilide A
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.806837/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.806837/full

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