Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack

Antiplatelet Resistance: A Review of Concepts, Mechanisms, and Implications for Management in Acute Ischemic Stroke and Transient Ischemic Attack

Acute ischemic stroke is a leading cause of death and major disability worldwide. Approximately 50% of ischemic strokes are caused by atherothrombotic occlusion of the cerebral arteries, and antiplatelets are the mainstay of secondary stroke preventative treatment. Aspirin is beneficial if given ear...

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Bibliographic Details
Main Authors: Kailash Krishnan, Thanh N. Nguyen, Jason P. Appleton, Zhe Kang Law, Mark Caulfied, Claudia P. Cabrera, Rob Lenthall, David Hewson, Timothy England, Norman McConachie, Permesh Dhillon, Luqman Malik, Anna Podlasek, Craig J. Smith, Jesse Dawson, Thompson G. Robinson, Nikola Sprigg, Martin A. James, Phil White, Michael J.R. Desborough, Joannes Hermans, Philip M. Bath
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Stroke: Vascular and Interventional Neurology
Subjects:
aspirin
clopidogrel
genetics
ischemic stroke
platelet function test
resistance
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.122.000576

Internet

https://www.ahajournals.org/doi/10.1161/SVIN.122.000576

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