Development and Qualification of an Antigen Integrity Assay for a <i>Plasmodium falciparum</i> Malaria Transmission Blocking Vaccine Candidate, Pfs230

Development and Qualification of an Antigen Integrity Assay for a <i>Plasmodium falciparum</i> Malaria Transmission Blocking Vaccine Candidate, Pfs230

During development of a subunit vaccine, monitoring integrity of the recombinant protein for process development and quality control is critical. Pfs230 is a leading malaria transmission blocking vaccine candidate and the first to reach a Phase 2 clinical trial. The Pfs230 protein is expressed on th...

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Bibliographic Details
Main Authors: Kazutoyo Miura, Thao P. Pham, Shwu-Maan Lee, Jordan Plieskatt, Ababacar Diouf, Issaka Sagara, Camila H. Coelho, Patrick E. Duffy, Yimin Wu, Carole A. Long
Format: Article
Language:English
Published: MDPI AG 2022-09-01
Series:Vaccines
Subjects:
subunit vaccine
integrity
potency
assay qualification
malaria
transmission-blocking vaccine
Online Access:https://www.mdpi.com/2076-393X/10/10/1628

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https://www.mdpi.com/2076-393X/10/10/1628

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