O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy

O-GlcNAcylation: an important post-translational modification and a potential therapeutic target for cancer therapy

Abstract O-linked β-d-N-acetylglucosamine (O-GlcNAc) is an important post-translational modification of serine or threonine residues on thousands of proteins in the nucleus and cytoplasm of all animals and plants. In eukaryotes, only two conserved enzymes are involved in this process. O-GlcNAc trans...

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Bibliographic Details
Main Authors: Qingsong Lu, Xiaozhen Zhang, Tingbo Liang, Xueli Bai
Format: Article
Language:English
Published: BMC 2022-09-01
Series:Molecular Medicine
Subjects:
O-GlcNAc
Post-translational modification
OGT
OGA
Biomarker
Cancer therapy
Online Access:https://doi.org/10.1186/s10020-022-00544-y

Internet

https://doi.org/10.1186/s10020-022-00544-y

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