Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development

Transient Nutrient Deprivation Promotes Macropinocytosis-Dependent Intracellular Bacterial Community Development

ABSTRACT Nutrient limitation restricts bacterial growth in privileged sites such as the middle ear. Transient heme-iron restriction of nontypeable Haemophilus influenzae (NTHI), the major causative agent of chronic and recurrent otitis media (OM), promotes new and diverse phenotypes that can influen...

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Bibliographic Details
Main Authors: Rachael L. Hardison, Derek R. Heimlich, Alistair Harrison, Wandy L. Beatty, Sarah Rains, M. Arthur Moseley, J. Will Thompson, Sheryl S. Justice, Kevin M. Mason
Format: Article
Language:English
Published: American Society for Microbiology 2018-10-01
Series:mSphere
Subjects:
Haemophilus
NTHI
endolysosomal pathway
host cell invasion
intracellular bacterial community
macropinocytosis
Online Access:https://journals.asm.org/doi/10.1128/mSphere.00286-18

Internet

https://journals.asm.org/doi/10.1128/mSphere.00286-18

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