TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p

TBX2 Drives Neuroendocrine Prostate Cancer through Exosome-Mediated Repression of miR-200c-3p

Deciphering the mechanisms that drive transdifferentiation to neuroendocrine prostate cancer (NEPC) is crucial to identifying novel therapeutic strategies against this lethal and aggressive subtype of advanced prostate cancer (PCa). Further, the role played by exosomal microRNAs (miRs) in mediating...

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Bibliographic Details
Main Authors: Girijesh Kumar Patel, Sayanika Dutta, Mosharaf Mahmud Syed, Sabarish Ramachandran, Monica Sharma, Venkatesh Rajamanickam, Vadivel Ganapathy, David J. DeGraff, Kevin Pruitt, Manisha Tripathi, Srinivas Nandana
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Cancers
Subjects:
exosomes
N-MYC
SOX2
TBX2
treatment-induced neuroendocrine prostate cancer
miR-200c-3p
Online Access:https://www.mdpi.com/2072-6694/13/19/5020

Internet

https://www.mdpi.com/2072-6694/13/19/5020

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