TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.

TIPRL Inhibits Protein Phosphatase 4 Activity and Promotes H2AX Phosphorylation in the DNA Damage Response.

Despite advances in our understanding of protein kinase regulation in the DNA damage response, the mechanism that controls protein phosphatase activity in this pathway is unclear. Unlike kinases, the activity and specificity of serine/threonine phosphatases is governed largely by their associated pr...

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Bibliographic Details
Main Authors: Kimberly Romero Rosales, Michael A Reid, Ying Yang, Thai Q Tran, Wen-I Wang, Xazmin Lowman, Min Pan, Mei Kong
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4696667?pdf=render

Internet

http://europepmc.org/articles/PMC4696667?pdf=render

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