Three-Component Coupling Reactions of Arynes for the Synthesis of Benzofurans and Coumarins
The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles. Coumarin derivative 5 was formed when diethyl malonate (2) or α-bromomalonate (3) were used as a C2-unit. In contrast, dihydrobenzo...
Main Authors: | Eito Yoshioka, Shigeru Kohtani, Hideto Miyabe |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2014-01-01
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Series: | Molecules |
Subjects: | |
Online Access: | http://www.mdpi.com/1420-3049/19/1/863 |
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