Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase

Antisense oligonucleotides conjugated with boron clusters (B-ASOs) have been described as potential gene expression inhibitors and carriers of boron for boron neutron capture therapy (BNCT), providing a dual-action therapeutic platform. In this study, we tested the nucleolytic stability of DNA oligo...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों: Damian Kaniowski, Katarzyna Kulik, Katarzyna Ebenryter-Olbińska, Ewelina Wielgus, Zbigniew Lesnikowski, Barbara Nawrot
स्वरूप: लेख
भाषा:English
प्रकाशित: MDPI AG 2020-05-01
श्रृंखला:Biomolecules
विषय:
ऑनलाइन पहुंच:https://www.mdpi.com/2218-273X/10/5/718