Metallacarborane Complex Boosts the Rate of DNA Oligonucleotide Hydrolysis in the Reaction Catalyzed by Snake Venom Phosphodiesterase
Antisense oligonucleotides conjugated with boron clusters (B-ASOs) have been described as potential gene expression inhibitors and carriers of boron for boron neutron capture therapy (BNCT), providing a dual-action therapeutic platform. In this study, we tested the nucleolytic stability of DNA oligo...
मुख्य लेखकों: | , , , , , |
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स्वरूप: | लेख |
भाषा: | English |
प्रकाशित: |
MDPI AG
2020-05-01
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श्रृंखला: | Biomolecules |
विषय: | |
ऑनलाइन पहुंच: | https://www.mdpi.com/2218-273X/10/5/718 |