beta1 integrin maintains integrity of the embryonic neocortical stem cell niche.

During embryogenesis, the neural stem cells (NSC) of the developing cerebral cortex are located in the ventricular zone (VZ) lining the cerebral ventricles. They exhibit apical and basal processes that contact the ventricular surface and the pial basement membrane, respectively. This unique architec...

Full description

Bibliographic Details
Main Authors: Karine Loulier, Justin D Lathia, Veronique Marthiens, Jenne Relucio, Mohamed R Mughal, Sung-Chun Tang, Turhan Coksaygan, Peter E Hall, Srinivasulu Chigurupati, Bruce Patton, Holly Colognato, Mahendra S Rao, Mark P Mattson, Tarik F Haydar, Charles Ffrench-Constant
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-08-01
Series:PLoS Biology
Online Access:http://europepmc.org/articles/PMC2720642?pdf=render