Circulating tumor cell characterization of lung cancer brain metastases in the cerebrospinal fluid through single‐cell transcriptome analysis

Circulating tumor cell characterization of lung cancer brain metastases in the cerebrospinal fluid through single‐cell transcriptome analysis

Abstract Background Brain metastases explain the majority of mortality associated with lung cancer, which is the leading cause of cancer death. Cytology analysis of the cerebrospinal fluid (CSF) remains the diagnostic gold standard, however, the circulating tumor cells (CTCs) in CSF (CSF‐CTCs) are n...

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Bibliographic Details
Main Authors: Haoyu Ruan, Yihang Zhou, Jie Shen, Yue Zhai, Ying Xu, Linyu Pi, Ruofan Huang, Kun Chen, Xiangyu Li, Weizhe Ma, Zhiyuan Wu, Xuan Deng, Xu Wang, Chao Zhang, Ming Guan
Format: Article
Language:English
Published: Wiley 2020-12-01
Series:Clinical and Translational Medicine
Subjects:
cerebrospinal fluid
circulating tumor cell
leptomeningeal metastases
lung adenocarcinoma
single‐cell RNA sequencing
Online Access:https://doi.org/10.1002/ctm2.246

Internet

https://doi.org/10.1002/ctm2.246

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