Neutrophil membrane fusogenic nanoliposomal leonurine for targeted ischemic stroke therapy via remodeling cerebral niche and restoring blood-brain barrier integrity

Neutrophil membrane fusogenic nanoliposomal leonurine for targeted ischemic stroke therapy via remodeling cerebral niche and restoring blood-brain barrier integrity

Ischemic stroke (IS) constitutes the leading cause of global morbidity and mortality. Neuroprotectants are essential to ameliorate the clinical prognosis, but their therapeutic outcomes are tremendously compromised by insufficient delivery to the ischemic lesion and intricate pathogenesis associated...

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Bibliographic Details
Main Authors: Zhuang Tang, Shiyu Meng, Zhiling Song, Xiaoxue Yang, Xinzhi Li, Hui Guo, Meirong Du, Jun Chen, Yi Zhun Zhu, Xiaolin Wang
Format: Article
Language:English
Published: Elsevier 2023-06-01
Series:Materials Today Bio
Subjects:
Neutrophil-mimetic
Leonurine
Ischemic stroke
Targeted therapy
Blood-brain barrier
Online Access:http://www.sciencedirect.com/science/article/pii/S2590006423001345

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http://www.sciencedirect.com/science/article/pii/S2590006423001345

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