Family-based gene-environment interaction using sequence kernel association test (FGE-SKAT) for complex quantitative traits
Abstract After the genome-wide association studies (GWAS) era, whole-genome sequencing is highly engaged in identifying the association of complex traits with rare variations. A score-based variance-component test has been proposed to identify common and rare genetic variants associated with complex...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2021-04-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-021-86871-2 |