Family-based gene-environment interaction using sequence kernel association test (FGE-SKAT) for complex quantitative traits

Abstract After the genome-wide association studies (GWAS) era, whole-genome sequencing is highly engaged in identifying the association of complex traits with rare variations. A score-based variance-component test has been proposed to identify common and rare genetic variants associated with complex...

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Bibliographic Details
Main Authors: Chao-Yu Guo, Reng-Hong Wang, Hsin-Chou Yang
Format: Article
Language:English
Published: Nature Portfolio 2021-04-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-86871-2