Teratogenic effects of lamotrigine on rat fetal brain: a morphometric study

A study of the teratogenic activity of an antiepileptic drug - lamotrigine - was carried out in the brain of fetuses of rats who had received the drug. The dosage levels studied corresponded to four times the median effective dose (ED50) in rats. The drug was administered during the organogenesis pe...

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Bibliographic Details
Main Authors: Nely Silvia Aragão de Marchi, Reinaldo Azoubel, Waldir Antonio Tognola
Format: Article
Language:English
Published: Academia Brasileira de Neurologia (ABNEURO) 2001-06-01
Series:Arquivos de Neuro-Psiquiatria
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0004-282X2001000300010&tlng=en